Início  /   Anti-lymphangiogenic properties of mTOR inhibitors in head and neck squamous cell carcinoma experimental models

Anti-lymphangiogenic properties of mTOR inhibitors in head and neck squamous cell carcinoma experimental models


Tumor dissemination to cervical lymph nodes via lymphatics represents the first step in the metastasis of head and neck squamous cell carcinoma (HNSCC) and is the most significant predictor of tumor recurrence decreasing survival by 50%. The lymphatic suppressing properties of mTOR inhibitors are not yet well understood.